Canada to Allow Vaccine Mixing for Second Doses

An advisory body approved following up AstraZeneca shots with either Pfizer-BioNTech or Moderna vaccines.,

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Canada will soon allow vaccine mixing for second doses.

A vaccination site administering the Pfizer vaccine in Canada last month. AstraZeneca shots are in short supply, so the country will soon begin administering the Pfizer-BioNTech or Moderna vaccines as a second dose.
A vaccination site administering the Pfizer vaccine in Canada last month. AstraZeneca shots are in short supply, so the country will soon begin administering the Pfizer-BioNTech or Moderna vaccines as a second dose. Credit…Carlos Osorio/Reuters
  • June 2, 2021, 6:13 p.m. ET

Facing vaccine shortages, Canada’s immunization advisory body is recommending some Canadians follow up their AstraZeneca shots with a different vaccine on the second dose.

The National Advisory Committee on Immunization said on Tuesday that people who received a first dose of the AstraZeneca vaccine can be given either the Pfizer-BioNTech or Moderna vaccines as their second dose. It also declared that the Pfizer and Moderna vaccines can be used interchangeably, although it recommended sticking with a single brand when possible.

While Canada’s health care system has generally been efficient in dispensing shots, no vaccines are manufactured in the country and larger shipments only began arriving over the past several weeks. To ensure that the maximum number of Canadians have some protection, Canada focused on getting at least one dose to as many people as possible. While 62 percent of Canadian adults have been given at least one shot, only 5.7 percent are fully vaccinated.

The advisory panel’s recommendation came as many provinces are starting to ramp up second doses and it may resolve a potential headache.

Most of the increased shipments of vaccine have come from Pfizer, while supplies of the Moderna and AstraZeneca vaccines have been in much shorter supply. To date, 19.3 million doses of Pfizer’s vaccine have come to Canada compared with 5.7 million doses of Moderna and just 2.8 million Astra Zeneca shots.

The ability to substitute Pfizer’s vaccine for second doses eliminates concerns about limited supplies.

The advisory panel said that its recommendation follows similar advice from Denmark, Finland, France, Germany, Sweden, Norway and Spain. Several studies have shown that mixing vaccines is safe and effective, the committee said.

Seven of Canada’s 10 provinces, whose health care systems perform the vaccinations, have said they will allow people to change course between doses.

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